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Research News from UC San Diego
Updated: 1 hour 54 min ago

Turning A Phage

Thu, 2018-06-21 08:40

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America’s first Center for Innovative Phage Applications and Therapeutics (IPATH).

Scripps Graduate Student Discovers World’s First Known Manta Ray Nursery

Mon, 2018-06-18 12:35

A graduate student at Scripps Institution of Oceanography at the University of California San Diego and colleagues from NOAA’s Office of National Marine Sanctuaries have discovered the world’s first known manta ray nursery. Located in the Gulf of Mexico off the coast of Texas at NOAA’s Flower Garden Banks National Marine Sanctuary, the juvenile manta ray habitat is the first of its kind to be described in a scientific study.

Greater Levels of Vitamin D Associated with Decreasing Risk of Breast Cancer

Fri, 2018-06-15 11:00

Researchers at University of California San Diego School of Medicine suggest higher levels of vitamin D are associated with decreasing risk of breast cancer. Their epidemiological study is published in the June 15 online issue of PLOS ONE, in collaboration with Creighton University, Medical University of South Carolina and GrassrootsHealth, an Encinitas-based nonprofit organization that promotes vitamin D research and its therapeutic benefits.

Greater Levels of Vitamin D Associated with Decreasing Risk of Breast Cancer

Fri, 2018-06-15 09:13

Researchers at University of California San Diego School of Medicine suggest higher levels of vitamin D are associated with decreasing risk of breast cancer. Their epidemiological study is published in the June 15 online issue of PLOS ONE, in collaboration with Creighton University, Medical University of South Carolina and GrassrootsHealth, an Encinitas-based nonprofit organization that promotes vitamin D research and its therapeutic benefits.

A Sprinkle of Platinum Nanoparticles Onto Graphene Makes Brain Probes More Sensitive

Thu, 2018-06-14 08:30

Graphene electrodes could enable higher quality imaging of brain cell activity thanks to new research by a team of engineers and neuroscientists at the University of California San Diego. The researchers developed a technique, using platinum nanoparticles, to lower the impedance of graphene electrodes by 100 times while keeping them transparent. In tests on transgenic mice, the electrodes were able to record and image neuronal activity (calcium ion spikes) at both the macroscale and single cell levels.

SDSC Comet and Machine Learning Simulates H2O with “Unprecedented Accuracy”

Wed, 2018-06-13 11:59

A team led by researchers at UC San Diego’s Department of Chemistry and Biochemistry and SDSC has used machine learning techniques to develop models for simulations of water with “unprecedented accuracy.” Published online in The Journal of Chemical Physics, the research demonstrates how popular ML techniques can be used to construct predictive molecular models based on quantum mechanical reference data.

UC San Diego Launches New Center for Anti-Parasitic Drug Discovery and Development

Wed, 2018-06-13 10:52

Neglected tropical diseases are a group of chronic and disabling parasitic infections that primarily affect poor and underserved communities. These diseases affect more than 1 billion people globally, yet are rarely the target of new drug discovery efforts. Leveraging its strengths in molecular biology, clinical research and pharmaceutical sciences, the University of California San Diego has now launched a new Center for Anti-Parasitic Drug Discovery and Development to address this unmet need in global health.

Engineer Receives Award From Energy Department to Advance Concentrating Solar Power Research

Tue, 2018-06-12 10:43

Renkun Chen, a professor of mechanical and aerospace engineering at the University of California San Diego, has received a $1.18 million dollar award from the U.S. Department of Energy Solar Energy Technologies Office to develop technology that can advance next-generation concentrating solar power (CSP) systems. The project is aimed at developing an ultra-sensitive infrared camera that can rapidly measure and monitor heat transfer in CSP plant materials and assess their performance over decades of use.

Composition of Complex Sugars in Breast Milk May Prevent Future Food Allergies

Tue, 2018-06-12 08:34

The unique composition of a mother’s breastmilk may help to reduce food sensitization in her infant, report researchers at the University of California San Diego School of Medicine with colleagues in Canada.

UC San Diego Ranked 3rd Among U.S. Public Universities in High-Quality Research

Thu, 2018-06-07 02:00

The University of California San Diego ranked 3rd among public research universities in the United States in this year’s annual ranking of high-quality scientific research papers by the journal Nature. In the Nature Index 2018 Annual Tables, the La Jolla campus ranked 12th in the world out of 500 institutions and 6th among U.S. universities in the research results its faculty, students and staff others published in 82 high-quality journals in 2017.

What’s Inside Your Medical Record?

Wed, 2018-06-06 12:19

Patients at UC San Diego Health can now read the medical notes signed by their primary care physician. This move toward transparency is part of an international trend to make patients feel more in control of their health care.

Antibody Blocks Inflammation, Protects Mice from Hardened Arteries and Liver Disease

Wed, 2018-06-06 11:13

Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL), molecules on cell surfaces that get modified by inflammation. Even while on a high-fat diet, the antibody protected the mice from arterial plaque formation, hardening of the arteries and liver disease, and prolonged their lives.

UC San Diego Tops List of World’s ‘Golden Age’ Universities

Wed, 2018-06-06 07:00

For the second year in a row, the London-based Times Higher Education ranked UC San Diego the world’s number one research university founded during the “golden age” of higher education development, in the two decades between 1945 and 1967—when higher education was characterized by rapid university expansion and increasing investment in research.

Phase I Trial Finds Experimental Drug Safe in Treating Chronic Lymphocytic Leukemia

Fri, 2018-06-01 08:00

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the “stemness” of chronic leukemia cancer (CLL) cells — their ability to self-renew and resist terminal differentiation and senescence.

Stem Cell-Based Phase I Trial to Repair Spinal Cord Injuries Produces Encouraging Results

Fri, 2018-06-01 08:00

Researchers at University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord injuries produced measurable improvement in three of four subjects, with no serious adverse effects.

Cell-like Nanorobots Clear Bacteria and Toxins From Blood

Wed, 2018-05-30 14:26

Engineers at the University of California San Diego have developed tiny ultrasound-powered robots that can swim through blood, removing harmful bacteria along with the toxins they produce. These proof-of-concept nanorobots could one day offer a safe and efficient way to detoxify and decontaminate biological fluids.

Single Injection Alleviates Chemotherapy Pain for Months in Mice

Tue, 2018-05-29 08:00

UC San Diego School of Medicine researchers found that treating mice with a single spinal injection of a protein called AIBP — and thus switching “off” TLR4, a pro-inflammatory molecule — prevented and reversed inflammation and cellular events associated with pain processing. As reported May 29 by Cell Reports, the treatment alleviated chemotherapy pain in mice for two months with no side effects.

UC San Diego Nets No. 20 Spot on New List of Globe’s Best Universities

Tue, 2018-05-29 07:00

A new world ranking names the University of California San Diego among the globe’s top 20 best universities; the campus netted the 16th spot on among U.S. universities. The annual rankings from the Center for World University Rankings (CWUR), released today, measure universities’ quality of research, faculty, influence, enterprise and successful alumni.

In a Break with Dogma, Myelin Boosts Neuron Growth in Spinal Cord Injuries

Wed, 2018-05-23 11:12

In a new paper, published in the May 23 online issue of Science Translational Medicine, researchers at University of California San Diego School of Medicine report that adult rat myelin actually stimulated axonal outgrowth in rat neural precursor cells (NPCs) and human induced pluripotent (iPSC)-derived neural stem cells (NSCs).

Physicists’ Room-Temperature Research Leads to ‘Exciting’ Possibilities for Science

Tue, 2018-05-22 12:01

As if taken from a Star Wars or Star Trek movie script, the term “exciton” (pronounced ˈek-sə-tän) comes from condensed matter physics. Excitons are bound states of electrons and electron holes attracted to each other by electrostatic force. They can be created both by light and transformed into light. Electrically neutral, these quasiparticles exist in systems like insulators and semiconductors, but University of California San Diego physicists have established a way that may bring them into future cell phones and laptops.

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