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Updated: 48 min 16 sec ago

Decoding the Genome’s Cryptic Language

Fri, 2017-02-24 14:13

Bioengineers at the University of California San Diego have developed a new tool to identify RNA-DNA interactions. The tool can provide a full account of all the RNA molecules that interact with a segment of DNA, as well as the locations of all these interactions — in just a single experiment. The research is a step toward identifying new functions and instructions encoded in the genome.

UC San Diego Organizes 2017 Workshop on Big Data and the Earth Sciences

Fri, 2017-02-24 09:18

Researchers in earth sciences and information technology at UC San Diego are organizing a three-day Grand Challenges workshop May 31 to June 2 in La Jolla, Calif., on the topic of “Big Data and the Earth Sciences.”

Transplanting Good Bacteria to Kill Staph

Wed, 2017-02-22 11:10

University of California San Diego School of Medicine researchers screened 10,000 colonies of bacteria found on the epidermis to determine how many had antimicrobial properties and at what rate these are found on healthy and non-healthy skin. In a paper published in Science Translation Medicine, the team reports isolating and growing good bacteria that produce antimicrobial peptides and successfully transplanting it to treat patients with the most common type of eczema, known as atopic dermatitis.

The FORCE11 Scholarly Communications Institute to Launch at UC San Diego

Tue, 2017-02-21 11:54

The global community of researchers, students, librarians, publishers, funders and scholars interested in the future of scholarship has announced the launch of its new annual Force 11 Scholarly Communications Institute, July 30-Aug. 4, 2017

Shedding Light on Cancer Diversity and Resistance

Tue, 2017-02-21 11:36

A paradigm-changing study in the journal Nature by cancer researchers and computer scientists at UC San Diego and other institutions found that short fragments of circular DNA that encode cancer genes are far more common in cancer cells than previously believed.

New Grant Boosts UC San Diego-Led Malaria Research Program

Fri, 2017-02-17 11:18

An international research team, led by principal investigator Elizabeth A. Winzeler, PhD, professor in the pediatric division of host-microbe systems and therapeutics at University of California San Diego School of Medicine, and colleagues have received a three-year, $4.7 million supplemental grant from the Bill & Melinda Gates Foundation to advance their development of improved therapies for malaria eradication and elimination.

‘Lossless’ Metamaterial Could Boost Efficiency of Lasers and Other Light-based Devices

Thu, 2017-02-16 14:46

Engineers at the University of California San Diego have developed a material that could reduce signal losses in photonic devices. The advance has the potential to boost the efficiency of various light-based technologies including fiber optic communication systems, lasers and photovoltaics.

Antibiotic Effective Against Drug-Resistant Bacteria in Pediatric Skin Infections

Thu, 2017-02-16 14:12

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial scourge that is resistant to most common antibiotics and thus difficult to treat, particularly in children where it commonly causes complicated skin and skin structure infections. In a randomized, controlled clinical trial — the first of its kind — a multi-institution research team reports that daptomycin, part of a new class of antibiotics currently approved only for use in adults, is effective and well-tolerated in children.

Analyzing Copies of Genes Offers New Treatment Possibilities for Ovarian Cancer

Wed, 2017-02-15 02:00

A team of 18 University of California San Diego School of Medicine and Moores Cancer Center researchers has developed a new tool to analyze an often overlooked aspect of cancer genetics — an alteration that results in the loss or gain in a copy of a gene. This change, known as somatic copy-number alterations, may be key to disease progression and might offer new therapeutic approaches for ovarian cancer and other malignancies.

Middle, Senior High Students Visit Ancient Sites in 3D – Without Leaving La Jolla

Tue, 2017-02-14 11:51

The Center for Cyber-Archaeology and Sustainability (CCAS) and the Qualcomm Institute played host to nearly 200 freshmen and older students taking computer science, robotics or AP world history at La Jolla Country Day School. The students converged on UC San Diego to learn more about how technology can safeguard the future of the ancient past.

Cancer Survivor and Noted Physician-Scientist Sandra Horning to Receive Roth Award

Tue, 2017-02-14 08:02

Sandra Horning, MD, Chief Medical Officer and executive vice president of global development for Roche and Genentech, a member of the Roche Group, has been named the 2017 recipient of the Duane Roth Memorial Award, which will be presented February 16 at the annual Industry/Academia Translational Oncology Symposium at UC San Diego Moores Cancer Center.

UC San Diego Electrical Engineer Accepts Alumni Award from Indian Alma Mater

Mon, 2017-02-13 12:13

UC San Diego distinguished professor of engineering Mohan Trivedi in the Electrical and Computer Engineering department has accepted the distinguished alumnus award from the Birla Institute of Technology and Science, Pilani, in the Indian state of Rajasthan. Trivedi returned to the campus for the first time in nearly 43 years to accept the honor.

Computer Scientist Wins Major Award from Computational Biology Society

Fri, 2017-02-10 14:22

The International Society of Computational Biology (ISCB) has announced the winners of its top four awards for 2017, and leading the list is UC San Diego computer-science professor Pavel Pevzner. The Accomplishments by a Senior Scientist Award honors Pevzner's almost 30 years in the field of bioinformatics, and in particular his significant contributions to research and education.

Innovators Wanted: UC Health Hack Seeks New Ideas to Solve Critical Health Problems

Thu, 2017-02-09 15:14

Think you have an idea that will change health care but need the means to bring your innovation to fruition? Register for UC Health Hack, a two-day interdisciplinary hackathon that will bring students, physicians, researchers, industry professionals and community members together to grapple with integrative medicine and global health issues in a fast-paced competition.

Gene Variant Identified for Kawasaki Disease Susceptibility

Thu, 2017-02-09 11:21

Researchers at University of California San Diego School of Medicine, with colleagues at Rady Children’s Institute for Genomic Medicine and in London and Singapore, have conducted novel whole genome sequencing of a family in which two of four children were affected by Kawasaki disease. They have identified plausible gene variants that predispose some children to developing the disease.

New method to identify bacteria in blood samples works in hours instead of days

Wed, 2017-02-08 15:38

Engineers at the University of California San Diego have developed a desktop diagnosis tool that detects the presence of harmful bacteria in a blood sample in a matter of hours instead of days.  The breakthrough was made possible by a combination of proprietary chemistry, innovative electrical engineering and high-end imaging and analysis techniques powered by machine learning.  The team details their work in the Feb. 8 issue of Nature Scientific Reports.

First Nuclear Explosion Helps Test Theory of Moon’s Formation

Wed, 2017-02-08 11:00

In a new study, Scripps Institution of Oceanography at the University of California San Diego Professor James Day and colleagues examined the chemical composition of zinc and other volatile elements contained in the green-colored glass, called trinitite, which were radioactive materials formed under the extreme temperatures that resulted from the 1945 plutonium bomb explosion, to examine theories about the Moon’s formation some 4.5 billion years ago.

UC San Diego Health Named Official Health Care Provider of the San Diego Padres

Tue, 2017-02-07 11:58

UC San Diego Health and the San Diego Padres reached an agreement on a multi-year partnership to become the Major League Baseball team’s Official Health Care Provider.

Study: Medicare Could Overpay Medicare Advantage Plans by $200 Billion Over Ten Years

Mon, 2017-02-06 14:14

Research conducted at University of California San Diego School of Medicine found that current trends in diagnostic coding for patient risk scores will lead to Medicare overpaying Medicare Advantage (MA) plans substantially through 2026-likely to the tune of hundreds of billions of dollars. The study is published in the February issue of Health Affairs.

Severe Newborn Jaundice Could be Preventable, Mouse Study Shows

Mon, 2017-02-06 12:32

In a mouse study, researchers at University of California San Diego School of Medicine have identified a protein that inhibits the enzyme that breaks down bilirubin in newborns. Methods that block this inhibitor, and thus restore the enzyme’s activity, could provide a new therapeutic approach for preventing or treating severe newborn jaundice. The study is published February 6, 2017 by the Proceedings of the National Academy of Sciences.

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